There is a new protagonist in the conversation about regenerative aesthetics: exosomes. They are microscopic vesicles —small packets of information that cells use to communicate— loaded with growth factors, proteins and signalling material.
A shift in approach
For years, much of aesthetic medicine focused on correcting: filling a fold, tightening a contour, concealing a spot. Regenerative aesthetics starts from a different question. Instead of replacing what the tissue has lost, is it possible to give it signals so that it rebuilds on its own? Exosomes come in through precisely that door.
They are not a filler or a volume product. They are information. And that difference changes how a treatment is planned: what we are after is not visible in the mirror on the way out of the office, but is built over time, as the cells respond. That is why, during the assessment with Dr. Sandro Florez in Bogotá, the conversation begins with the patient's goals and with the real state of their skin or scalp, not with the name of the product.
Why so much interest?
Because they act as messengers: when applied to the skin or the scalp (usually combined with microneedling to improve their penetration), they deliver those signals directly to the cells that need them, stimulating repair, collagen production and, in hair, follicular activity.
That mechanism also explains why the route of application matters so much. Skin is designed to be a barrier, and a barrier that works well does not let large molecules in easily. Microneedling opens temporary micro-channels that allow the product to reach the plane where it can be useful. Applying exosomes without that preparation, or with an inadequate technique, changes the logic of the treatment entirely.
Skin and hair
On the face
On the face, exosomes are used to improve texture, luminosity and recovery after procedures such as microneedling or laser: the skin calms down sooner and responds better.
That is why they fit well within a facial treatment plan designed in stages, rather than as an isolated gesture. In well-selected patients, they are often added to anti-ageing strategies where the goal is tissue quality —how the skin looks and how it behaves— more than a change of features.
On the scalp
On the scalp, early studies suggest that combining exosomes with microneedling enhances follicular stimulation beyond what is achieved with PRP alone; that is why they are being integrated into alopecia management protocols.
It helps to understand their place: they are a stimulation tool, not a replacement for what a hair transplant does when the follicle is no longer there. In many cases, both are sequenced over time within a single plan.
Do they replace PRP?
Not necessarily: they complement each other. Platelet-rich plasma contributes your own growth factors; exosomes add more concentrated and standardised signalling. The right combination depends on each patient, and that is defined in a medical assessment.
The useful question, then, is not which one is better in the abstract, but which one suits this patient, at this moment and with this goal. That decision should not be made from a catalogue.
Who they are for and who they are not for
In general terms, candidates tend to be people looking to:
- Improve skin texture and luminosity without changing their features.
- Support recovery after procedures such as microneedling or laser.
- Add stimulation within a hair plan already defined by the physician.
- Work on tissue quality with a medium-term perspective.
On the other hand, the case should be reviewed calmly —or the procedure ruled out— when there is infection or active lesions in the area to be treated, undiagnosed skin or scalp disease, medical conditions requiring prior management, pregnancy or breastfeeding, or expectations that do not match what the treatment can offer. Each of these situations is assessed individually: the contraindication is defined by the physician during the assessment, not by a general list.
How it is done in the office
At the office on Calle 126 # 7-26, Torre 126 PH-1303, in Bogotá, the session follows an ordered sequence:
- Medical assessment. Clinical history, review of the skin or scalp and definition of the goal. This is where it is decided whether exosomes genuinely add something to the case.
- Preparation. Cleansing and asepsis of the area. The physician determines whether any comfort measure is needed before starting.
- Microneedling. Performed to open the route of entry and prepare the tissue.
- Application of the exosomes. Onto the already prepared skin or scalp, always with products of certified quality.
- Instructions and follow-up. Aftercare and scheduling of the next check-up.
What to expect
It is reasonable to expect a process, not an immediate before and after. Since the aim is to stimulate the tissue's own repair, changes are usually perceived progressively and vary from patient to patient: age, starting condition, habits and consistency with the plan weigh as much as the procedure itself. No regenerative treatment guarantees a result, and any promise of that kind should raise a warning.
It is also normal for the treated area to look sensitive or reddened during the first hours, especially because of the microneedling. The physician explains in each case what is expected and what is not.
Aftercare
- Follow the instructions given in the office to the letter.
- Avoid direct sun exposure and use sun protection consistently.
- Do not apply products or actives that have not been authorised by the physician.
- Respect the indicated intervals before resuming other procedures.
- Get in touch if any unanticipated sign appears.
When it is not the best option
There are scenarios in which exosomes, however good they may be, are not the answer. When the issue is volume or structural support, the tool is a different one. When hair loss is advanced and the follicle no longer responds, the path may be surgical and is assessed within hair transplant or other plastic surgery alternatives depending on the case. When there is an untreated medical cause behind the deterioration of the skin or hair, starting with stimulation means starting at the end.
And when what the patient expects is an immediate transformation, the honest thing is to say so beforehand: this is not that kind of treatment.
Our vision
The aesthetics that lie ahead are not about transforming faces, but about giving tissues back their capacity to repair themselves. Exosomes are a powerful tool within that philosophy, always with products of certified quality and in medical hands.
If you want to know whether they make sense in your case, the starting point is an assessment with Dr. Sandro Florez. You can review the full picture in treatments or book your appointment in Bogotá.
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